解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::A detailed structural diversity of dienoic fatty acids (FA), including non-methylene-interrupted dienoic FA, of triacylglycerols and polar lipids in ovaries of Cellana toreuma was clarified for the first time by using capillary gas chromatography-mass spectrometry of their 3-pyridylcarbinol esters and argentation thin...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-015-4107-8
更新日期:2016-02-01 00:00:00
abstract::This study analyses the effects of dietary lipid level and source on lipid absorption and metabolism in Senegalese sole (Solea senegalensis). Juvenile fish were fed 4 experimental diets containing either 100 % fish oil (FO) or 25 % FO and 75 % vegetable oil (VO; rapeseed, linseed and soybean oils) at two lipid levels ...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-015-4089-6
更新日期:2016-01-01 00:00:00
abstract::Carbohydrate response element binding protein (ChREBP) regulates insulin-independent de novo lipogenesis. Recently, a novel ChREBPβ isoform was identified. The purpose of the current study was to define the effect of dietary carbohydrates (CHO) and obesity on the transcriptional activity of ChREBP isoforms and their r...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-015-4090-0
更新日期:2016-01-01 00:00:00
abstract::The schweinfurthins have potent antiproliferative activity in multiple glioblastoma multiforme (GBM) cell lines; however, the mechanism by which growth is impeded is not fully understood. Previously, we demonstrated that the schweinfurthins reduce the level of key isoprenoid intermediates in the cholesterol biosynthet...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-015-4083-z
更新日期:2015-12-01 00:00:00
abstract::Vegetable oils are an extremely important agricultural commodity. Their use has risen inexorably for the last 50 years and will undoubtedly be even more prevalent in the future. They have a role not only in foodstuffs but also as renewable chemicals. However, our understanding of their metabolism, and particularly its...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-015-4069-x
更新日期:2015-11-01 00:00:00
abstract::Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disorder. Stress promotes the onset of the NAFLD with a concomitant increment in the activity of the hepatic 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1). However, the interaction between the stress and a carbohydrate-enriched diet for t...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-015-4066-0
更新日期:2015-11-01 00:00:00
abstract::Unsaturated free fatty acids (FFA) are able to prevent deleterious effects of saturated FFA in skeletal muscle cells although the mechanisms involved are still not completely understood. FFA act as endogenous ligands of peroxisome proliferator-activated receptors (PPAR), transcription factors regulating the expression...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-015-4058-0
更新日期:2015-10-01 00:00:00
abstract::We previously reported that phospholipids markedly affected the uptake of carotenoids solubilized in mixed micelles by human intestinal Caco-2 cells. In the present study, we found that two classes of dietary glyceroglycolipids and the corresponding lysoglyceroglycolipids affected uptake of β-carotene and lutein by di...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-015-4033-9
更新日期:2015-09-01 00:00:00
abstract::Usually, the chemical structures of cerebrosides in sea creatures are more complicated than those from terrestrial plants and animals. Very little is known about the method for high-throughput molecular profiling of cerebrosides in sea cucumbers. In this study, cerebrosides from four species of edible sea cucumbers, s...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-015-4039-3
更新日期:2015-07-01 00:00:00
abstract::In offspring exposed in utero to a maternal diet high in fat (HF), we have previously demonstrated that despite similar birth weights, HF adult offspring at 6 months of age had significantly higher body weights, greater adiposity, and increased triacylglycerol (TAG) levels as compared to controls. We hypothesized that...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-015-4018-8
更新日期:2015-06-01 00:00:00
abstract::Most CLA chicken feeding trials used cis,trans (c,t) and trans,cis (t,c) CLA isomers to produce CLA-rich eggs, while reports of trans,trans (t,t) CLA enrichment in egg yolks are limited. The CLA yolk fatty acid profile changes and the 10-12 days of feeding needed for maximum CLA are well documented, but there is no in...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-015-3996-x
更新日期:2015-04-01 00:00:00
abstract::Cyclic fatty acid monomers (CFAM) are mainly formed during heat treatments, such as frying, of edible oils. These fatty acids are mixtures of disubstituted five- or six-carbon-membered ring structures. Some earlier studies have suggested that some of these molecules could be metabolized and detoxified, but so far, nei...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-015-3997-9
更新日期:2015-04-01 00:00:00
abstract::Polar lipids of bacteria from the class Thermomicrobia are known to contain long-chain 1,2-diols instead of glycerol, although the nature of polar head groups has not been investigated. We have studied phospholipid classes of two species from the class Thermomicrobia-Sphaerobacter thermophilus and Thermomicrobia sp. W...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-014-3979-3
更新日期:2015-03-01 00:00:00
abstract::The aim of this study was to determine the influence of long-term docosahexaenoic acid (DHA) dietary supplementation on the erythrocyte fatty acid profile and oxidative balance in soccer players after training and acute exercise. Fifteen volunteer male athletes (age 20.0 ± 0.5 years) were randomly assigned to a placeb...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-014-3976-6
更新日期:2015-02-01 00:00:00
abstract::A maternal high fat diet (HFD) can have adverse effects on skeletal muscle development. Skeletal muscle PLIN proteins (PLIN2, 3 and 5) are thought to play critical roles in lipid metabolism, however effects of HFD on PLIN and lipases (HSL, ATGL, CGI-58) in mothers as well as their offspring have yet to be investigated...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-014-3985-5
更新日期:2015-02-01 00:00:00
abstract::Lipases catalyze the hydrolysis and synthesis of triglycerides and their reactions are widely used in industry. The use of ionic liquids has been explored in order to improve their catalytic properties. However, the effect of these compounds on kinetic parameters of lipases has been poorly understood. A study of the k...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-014-3973-9
更新日期:2015-01-01 00:00:00
abstract::Ceramides are a family of signalling lipids with diverse physiological functions that include pro-differentiative and pro-apoptotic signalling. Ceramides and their derivatives are major constituents of myelin, maintaining neuronal conductivity. Ceramides are synthesized by ceramide synthases, of which there are six is...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-014-3969-5
更新日期:2015-01-01 00:00:00
abstract::This study investigates the protective effect of N-stearoylethanolamine (NSE), a bioactive N-acylethanolamine , on the lipid profile distribution in the pancreas of obesity-induced insulin resistant (IR) rats fed with prolonged high fat diet (58% of fat for 6 months). The phospholipid composition was determined using ...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-014-3960-1
更新日期:2015-01-01 00:00:00
abstract::Recent reports show that a fatty meal can substantially increase the concentration of oxidized lipids in low density lipoprotein (LDL). Knowing the LDL-specific antioxidant effects of high density lipoprotein (HDL), we aimed to investigate whether HDL can modify the postprandial oxidative stress after a fatty meal. Su...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-014-3963-y
更新日期:2014-12-01 00:00:00
abstract::Bioassay-guided fractionation of a collection of Moorea bouillonii from Papua New Guinea led to the isolation of a new alkyl amide, mooreamide A (1), along with the cytotoxic apratoxins A-C and E. The planar structure of 1 was elucidated by NMR spectroscopy and mass spectrometry analysis. Structural homology between m...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-014-3949-9
更新日期:2014-11-01 00:00:00
abstract::Type 2 diabetes mellitus (T2DM) often occurs concurrently with high blood cholesterol or dyslipidemia. Although T2DM has been hypothesized to impair bone microstructure, several investigations showed that, when compared to age-matched healthy individuals, T2DM patients had normal or relatively high bone mineral densit...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-014-3950-3
更新日期:2014-10-01 00:00:00
abstract::This study proposed lipid fingerprinting of human seminal plasma by mass spectrometry as an analytical method to differentiate biological conditions. For this purpose, we chose infertile men as a model to study specific conditions, namely: high and low seminal plasma lipid peroxidation levels (sub-study 1.1), high and...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-014-3922-7
更新日期:2014-09-01 00:00:00
abstract::Choline is an essential nutrient required for the biosynthesis of membrane lipid phosphatidylcholine (PtdCho). Here we elucidate the mechanism of how palmitic acid (PAM) and oleic acid (OLA) regulate choline transporter-like protein 1 (CTL1/SLC44A1) function. We evaluated the mechanism of extracellular and intracellul...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-014-3925-4
更新日期:2014-08-01 00:00:00
abstract::A methodology combining finger-pricked blood sampling, microwave accelerated fatty acid assay, fast gas chromatography data acquisition, and automated data processing was developed, evaluated and applied to a population study. Finger-pricked blood was collected on filter paper previously impregnated with 0.05 mg of th...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-014-3918-3
更新日期:2014-08-01 00:00:00
abstract::Southern bluefin tuna (SBT, Thunnus maccoyii) aquaculture is a highly valuable industry, but research on these fish is hampered by strict catch quotas and the limited success of captive breeding. To address these limitations, we have developed a SBT cell line (SBT-E1) and here we report on fatty acid metabolism in thi...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-014-3910-y
更新日期:2014-07-01 00:00:00
abstract::Acetate supplementation increases plasma acetate, brain acetyl-CoA, histone acetylation, phosphocreatine levels, and is anti-inflammatory in models of neuroinflammation and neuroborreliosis. Although radiolabeled acetate is incorporated into the cellular lipid pools, the effect that acetate supplementation has on lipi...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-014-3911-x
更新日期:2014-07-01 00:00:00
abstract::Uptake of oxidized low-density lipoprotein by endothelial cells is a critical step for the initiation of atherosclerosis. Triacylglycerol uptake in these cells is understood to be a part of the process. The present investigation, comparison among the effects of simple acylglycerol, including tristearin, triolein, and ...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-014-3889-4
更新日期:2014-05-01 00:00:00
abstract::Plasma fatty acid (FA) composition is known to be an indicator of dietary fat quality, but the associations of other dietary factors with plasma FA composition remain unknown in children. We investigated the cross-sectional associations of food consumption with the proportions of FA and estimated desaturase activities...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-014-3894-7
更新日期:2014-05-01 00:00:00
abstract::In the present study we evaluated the uptake of ALA and its conversion to EPA + DHA in rats given linseed oil (LSO) in native form or as a microemulsion in whey protein or in lipoid. In a single oral dose study in which rats maintained on rodent pellets deficient in ω-3 fatty acids were intubated with 0.35 g LSO in li...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-013-3873-4
更新日期:2014-03-01 00:00:00
abstract::The molecular species of sphingoid bases were tagged with the fluorescent amino group reagent, 4-fluoro-7-nitrobenzofurazan (NBD-F). The NBD-sphingoid bases were analyzed by a highly selective and sensitive liquid chromatography-electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) technique capable of relia...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-013-3871-6
更新日期:2014-03-01 00:00:00
abstract::The current study evaluated the composition and relationships of polyunsaturated fatty acid biohydrogenation products (PUFA-BHP) from the perirenal (PRF) and subcutaneous fat (SCF) of yearling steers fed a 70 % grass hay diet with concentrates containing either sunflower-seed (SS) or flaxseed (FS). Analysis of varianc...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-013-3876-1
更新日期:2014-03-01 00:00:00
abstract::The present study was conducted to evaluate the ontogeny and kinetic of CPT I in several tissues of the Chinese sucker Myxocyprinus asiaticus. To this end, liver, muscle and intestine tissues were examined at five various developmental stages of Chinese sucker: newly-hatched larvae, 68-day-old, 4-month-old, 1- and 2-y...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-013-3864-5
更新日期:2014-02-01 00:00:00
abstract::Neutrophils play a major role in inflammation by releasing large amounts of reactive oxygen species (ROS) produced by NADPH oxidase (NOX) and myeloperoxidase (MPO). This ROS overproduction is mediated by phosphorylation of the NOX subunits in an uncontrolled manner. Therefore, targeting neutrophil subunits would repre...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-013-3863-6
更新日期:2014-01-01 00:00:00
abstract::The presence of leptin receptors in white adipose tissue (WAT) suggests a type of peripheral control during the development of obesity and other metabolic disorders. Both diet composition and exercise influence serum leptin; however, the effect of their combination on long-term WAT leptin metabolism is unknown. In thi...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-013-3854-7
更新日期:2014-01-01 00:00:00
abstract::Although hypocholesterolemia is a reported finding in sickle cell disease (SCD), low-density lipoprotein (LDL)/high-density lipoprotein (HDL) subfractions and HDL-associated enzymes have not been determined in SCD patients. Blood was collected from 38 hemoglobin (Hb)A volunteers and 45 homozygous HbSS patients who had...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-013-3849-4
更新日期:2013-12-01 00:00:00
abstract::Some studies focused on the effect of the dietary glycemic index on lipoproteins and apolipoproteins in adults; however, little evidence exists among adolescents regarding the effect of a low glycemic index (LGI) diet on apolipoproteins and lipoprotein (a) (Lpa). This study was conducted to evaluate the effect of an L...
journal_title:Lipids
pub_type: 杂志文章,随机对照试验
doi:10.1007/s11745-013-3834-y
更新日期:2013-12-01 00:00:00
abstract::Conjugated linoleic acid (CLA) has been shown to cause a reduction in obesity in several species. CLA-induced body fat loss is enhanced when mice are fed coconut oil (CO) and involves increased lipolysis. The objective of this paper was to determine if the CLA-induced lipolysis in mice fed with different oil sources w...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-013-3835-x
更新日期:2013-11-01 00:00:00
abstract::Phospholipids are integral constituents of the milk fat globule membranes and they play a central role in infants' immune and inflammatory responses. A methodology employing liquid chromatography coupled with evaporative light scattering detector has been optimized and validated to quantify the major phospholipids cla...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-013-3825-z
更新日期:2013-10-01 00:00:00
abstract::We examined growth performance and the lipid content in juvenile cobia, Rachycentron canadum, fed a taurine supplemented (1.5 %), plant protein based diet with two fish oil replacements. The first fish oil replacement was a thraustochytrid meal (TM + SOY) plus soybean oil (~9 % CL) and the second was a canola oil supp...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-013-3814-2
更新日期:2013-09-01 00:00:00
abstract::The aim of this study was to determine the effects of an omega-3 (n-3) polyunsaturated fatty acid (PUFA)-enriched diet on animal fat depots and lipid oxidation in the blood and meat of broiler chickens. Abdominal fat pad (AFP), sartorius muscle and liver histology were used to assess the effect of the dietary fat on a...
journal_title:Lipids
pub_type: 杂志文章
doi:10.1007/s11745-013-3785-3
更新日期:2013-07-01 00:00:00